Main scientific interest of Dr. Galgani is focused on the comprehension of the biological and molecular mechanisms regulating the immune system in autoimmune diseases, cancer and auto-inflammatory conditions. In particular, his main interest concerns the study of the pathogenic mechanisms leading to the alteration of immune tolerance during autoimmune diseases, such as Type 1 Diabetes (T1D). Dr. Galgani aims at studying the functional characteristics T cells involved in the control of immune tolerance. Specifically, the research is focused on the study of the role of metabolic programs (glycolysis and FAO) in the control of regulatory cell function.
In addition, the research area of Dr. Galgani is also focused on the comprehension of pathogenic mechanisms at the basis of T1D, and, in particular, on the identification of novel biomarkers reflecting diabetes onset and progression.
